What’s Actually Going On in Your Skin When It Flares?

What’s Actually Going On in Your Skin When It Flares?

Under the Microscope: The Science of Rosacea

To heal rosacea, you must understand it. Rosacea is more than redness—it’s a disorder of immune imbalance, nerve hypersensitivity, and dysfunctional skin signaling. Here’s what really happens in a flare-up.

The Cascade of Chaos:

  • TLR2 Overactivation: Toll-Like Receptor 2, part of your skin’s immune defense, is hyperactive in rosacea, triggering unnecessary inflammatory responses.

  • Kallikrein 5 & Cathelicidin LL-37: This enzyme-cathelidicin duo becomes overexpressed. LL-37, while meant to protect, actually increases inflammation and dilates blood vessels.

  • Flawed Feedback Loop: The more your skin flushes, the more it triggers itself. Nerves, immune cells, and blood vessels keep amplifying the signal.

  • Barrier Breakdown: This makes skin hypersensitive, prone to stinging, and more vulnerable to the environment.

Why Standard Products Fail: Most products ignore the immune/neurological drivers. Rosacea skin isn’t just dry—it’s misfiring on multiple systems.

How Roccoco Intervenes: We don’t suppress symptoms—we retrain the skin’s responses with:

  • Helichrysum: Neurocalming

  • Hops: Anti-inflammatory and antimicrobial

  • Ceramides + Phytosterols: Rebuild barrier integrity

Try This:

  • Reactive Skin Serum + Radiance Moisturiser: A synergy that soothes skin, downregulates inflammatory peptides, and protects the dermal matrix.

Next: We’ll show you the Roccoco Rosacea Ritual and why it works faster than traditional topicals.


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